Other than that, it's extremely cheap, seems to have a very favorable risk profile, and is at least in the same ballpark as Minoxidil in regards to efficacy. Something that will be asked is how oral castor oil compares to traditional treatment options. 7) Leven Rose. As far as the other compounds, Seti was sadly recently dropped from clinical trial pipeline after the underwhelming clinical trial data. Oral castor oil is also a no brainer for me personally based on the safety data, cost, efficacy, etc. When you compare them to one another, Minoxidil will win hands down in efficacy. I agree with you regarding the efficacy of CB-03-01, I don’t think it will be a long term maintenance option. The people who are so critical about fin should just go to r/bald. Bob, are you using castor oil capsules? The only limiting side effect of castor oil that I'm aware of as of now is its gastrointestinal effects that may not be tolerable for all individuals. What would you use for PGD2 inhbition? In practical application though, oral castor oil actually seems to work better than literal topical PGE2. Since I posted this article, a couple testimonials were commented on the YouTube video that I felt were worth including as well. The 2 most effective in my opinion are Minoxidil and MK-677. When it comes to growth promoting agents, I believe that oral castor oil is one of the most cost-effective and well-tolerated options there is for a beginner. I have the same questions as Infernox as well. Do you keep it in the fridge? Apparently in other countries, castor oil is used in both male/female contraceptives? Ill be honest, i didnt care much about your hair loss stuff until i noticed that now i can see my scalp very easy (specially when wet), whereas before i wasnt. While he's not particularly concerned with hair loss prevention, the results he reports are still useful to reference as the mechanism by which beard hair growth is facilitated is not different than on the scalp, it just doesn't have a cascade of hypoxia triggering factors causing miniaturization like on the scalp via androgens. 1180 products found Refine by AS I AM Jamaican Black Castor Oil Water. I really want to try this treatment but for price I don’t want to be below baseline in just 12 months. And for those who are willing to manipulate their hormones a bit more, or use higher risk treatment options, castor oil is still something I see as a potentially low risk addition to help solidify a strong, comprehensive regimen. There are so many benefits that Castor seed oil is famous for. In practical application, its effect on hair loss prevention topically seems to be minimal when it comes to dealing with androgenic alopecia as opposed to a skin condition. But, is that really a long-term sustainable practice just for hair density? We only know about the hair growth benefits of castor oil from hearsay, people’s personal accounts of their experience with the oil, and cultural traditions. They can be used in conjunction with one another for an even better effect. NOW Solutions Castor Oil is third party tested and meets our criteria for a high quality Castor Oil, and is also what I use personally. Some guys can’t sleep at all when they use it. With that said, what is my best bet since I caught my balding relatively early? Does it matter if I take castor oil with food, or should it only be taken on an empty stomach? We already know that the way castor oil facilitates its potential benefits in a hair loss prevention context is via the formation of PGE2 and activation of some of the same receptors as PGE2. But there is so much fear mongering among the people here about the most effective hair loss treatment we have. This is what I noticed personally using at least 1 mL per day for 2 months straight. All very cost prohibitive options unfortunately, but there is recent safety data for you to reference. Best Castor Oil for Hair Growth. It should be noted that I don't recommend using this high of a dose, but it is insightful to reference his results at 5 mL nonetheless. I will be experimenting with 1 mL per day myself, and will make a judgment after I've given it a fair chance as to whether or not I think it holds its own to justify its use in a hair loss prevention capacity for most men. The researchers found that topical castor oil may increase hair luster. NOW Solutions Castor Oil is third party tested and meets our criteria for a high quality Castor Oil, and is also what I use personally. I'm keeping it in my protocol for now and for the foreseeable future. Castor oil has anti-microbial properties, that will help you get rid of dandruff and other scalp issues. Also, do you think it’s strong enough to keep people at baseline long term when used as a monothearpy? Moreover, Castor seed oil is very reliable and much beneficial for hair, skin, and oral care. However, I am still wary of any potential long-term ramifications it could have on gut health in particular, and will proceed with caution. With that being said, growth promoting options that appear to be fairly low risk (like microneedling) make sense to deploy concurrently with whichever strategy you have in mind for tackling androgens off the bat. The compound accomplishes what its meant to do, but it will not replace anti-androgens, or other compounds meant to do completely different things in the body. I think my hair might even be getting a bit darker too, but that could just be me seeing things. In theory, this could help relieve hair follicle hypoxia by antagonizing the tissue constricting effects of Prostaglandin D2 (PGD2) in the scalp [R]. Food/Pharma grade (USP or BP) is ideal as it ensures a high enough standardization of Ricinoleic acid. The reason why is that both of these compounds increase circulation to the scalp, thereby alleviating the follicular miniaturization occurring in the tissue. Is any of this concerning to you? So, there is a possibility that the more you can tolerate the better it will be for hair, but that will be individual dependent at the end of the day, and will only be determined via personal experimentation. When it comes to digestive issues, I've had none so far using as much as 1.5 to 2 milliliters per day. There’s tons of other topical anti androgens I’ve read, but almost all of them are pretty much guaranteed to cause systemic problems. Did you know that the mouth is one of the most important parts of the body when it comes to your health? PGE2 is also cost prohibitive, whereas castor oil is dirt cheap, seems to facilitate much of the same effects at a fraction of the price, and there is a lot of data supporting the safety of the consumption of castor oil at dosages far exceeding what someone would consume in a hair loss prevention context. As a laxative, doses above 5 mL are commonly used, although many will assert that anything above a 2 mL daily dose will cause the same laxative effects. Female rats injected with castor oil after estus had anti-implantation and abortive effects. Takes a while to dissolve though. 3) Tropic Isle Living Jamaican Black Castor Oil. Castor oil is literally 1/1000th the price (maybe even less). I agree with you that the PGD2/PGE2 angle is not as effective as targeting androgens, which is why I’m starting to lean towards a topical anti-androgen. Androgens are still wreaking havoc on your hair even when Minoxidil is in your system if you do not have something in your protocol that addresses androgens directly, or a part of the cascade that occurs as a consequence of androgens. Ricinoleic acid induces formation of Prostaglandin E2 (PGE2) and acts as a potent agonist of EP3 and EP4 receptors [R, R]. Derek how many calories does this oil contain? Nearly all dosing groups returned to baseline, and one can imagine if the study was ran for an extra 6 months they would all be below baseline? Setipiprant, OC000459, or Fevipiprant. 8) Shiny Leaf. In recent years, more and more beauty enthusiasts have begun praising castor oil as a natural solution for hair growth. Castor oil operates via a totally different mechanism of action and cannot be compared to things like Finasteride, or Dutasteride, or RU58841, or even PGD2 inhibitors. Or can you mix it to tolerate it? 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